The Bills offense is largely non-existent, but Peterman is just so bad McDermott has no choice but to start Anderson. He hasn't had much time to get up to speed, but he did work with OC Brain Daboll back in Cleveland in 2009. I'd be careful of the Bills defense. They've were ranked 18th in week three and have moved up to being ranked third now. The first six quarters of the season were a disaster, but they've been playing very well since then. They kept the Bills in the game last week in Houston (two interceptions and a fumble recovery), and with any offense at all the Bills would've won that game. As someone who watches the Bills every week I don't see a huge downgrade going from Josh Allen to Anderson, they were running a pretty simplified playbook already because the rookie was learning on the job.