alternate runlines can be very valuable in some cases. I like to use the +1.5 line in games that Santana is a -300 fav. You can still get plus money on the dog, and Santanna has won 4 games this year by exactly 1 run.
Taking that run is IMO the way to go. People really underestimate how many 1 run games there are in baseball. If you have a great starter I would lay it anytime.