I used to work in Piitsburg (a few years back), it sucked. Dout MInny is any great shakes either.
I have vacationed in VA Beach, and it seemed like a nice area.
I have lived in Philly my whole life and would recomend it to anyone.
Great college and Pro sports, minor league sports (baseball, indoor soccer, arena football) as well. Awesome restuarants (not as many as NYC, especially ethnic offerings), and plenty of non gamling activities (concerts, shows, plays, museams). Close to the mountains for skiing, NJ beaches (I prefer OC MD and VA Beachmyself), AC casinos. If you live in the suburbs, there are fantastic public schools, and the taxes are not bad at all. RE has gone through the roof, my 4BR has increased about 80% in the last 4 years, but is tapering off now (not going down but going up slower). Awesome education (colleges) and medical facilites.
Good luck whatever you decide.