Yes, I've been in a league for the past 5 or 6 years. We now use U-Sports.com for the league (in the past, our commissioner had to grade each player/team manually!). The site had some hiccups the first year we used it (U-Sports), but worked nicely last year.
College fantasy football, IMO, is light years better than pro! More teams to choose from, many more players, and in contrast to the NFL, every year there are many, many players that turn out to be great acquisitions (that no one knew about at draft time). Makes Saturdays SOOOOOO much more fun!! (and yes, much more work than pro -- in a good way)