Be careful in YBOR city after dusk..........they have been having major violence in that area over the last few months which includes multiple murders.
YBOR is only dangerous if you wander outside the club area/main streets.
I used to work in Ybor at Club Skye when I was in college.
Ybor is definitly the place to go if you're from the ages of 18-30. There are numerous places to go, maybe 20 clubs/bars and they're all within a 4-5 street radius. Thursday/Friday/Saturday it's packed. Just check out who's going in what if this is your thing because there are your black/hiphop clubs, raggeton/latina clubs, trance club, everything club, and then more low key bars/clubs. Don't want to waste a cover.
If you're looking for something more lowkey, than check out Channelside. There are a few bars and restaurants, generally the 30+ crowd.
Be careful of DUI's in TAMPA. I've lived in 5 different places in the US, 3 in Florida alone, and they have more pigs than a fucking farm. You'll be thrown in the cell down @ Orient Rd. for next to nothing.