The best way to make money in MB is to look for in-game wagering IMO. I made a ton (and lost a ton) last year by taking big dogs in-game when they were down large and hoped for them to comeback. Just 1 come-back at +10000 goes a long, long way. I normally start "buying" a team when they are +500 .... then hope for a rally where I can sell the team at +200, and "scalp" out the difference to have a position on both sides of the game, not making a damn difference who wins or looses.
It takes a long time to get comfortable with the way MB goes, but when you do, it's like crack.